Shanghai FDC-CHEMICAL Co., Ltd.
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Country: 
China (Mainland)
Business Type:Trading Company
Tel: 86-21-61469567
Mobile:
Tel: 86-21-61469567
Fax: 86-21-61469151
URL: https://www.fdc-chemical.com/
Province/state: Shanghai
City: Shanghai
Street: Room 1101, Building A8, Lane 1688, North Guoquan Road, Yangpu District, Shanghai
MaxCard:
CAS NO.4424-20-8
Our R&D center is located in the Hongqiao Science andTechnology Innovation Park, Songjiang District, Shang-hai. The center is fully operated with four chemicalsynthesis laboratories and two kilo-lab laboratories.Our production facilities, located in Shandong, Jiang-su, and Hebei, are capable of handling the productionof advanced pharmaceutical intermediates, rangingfrom 100 kg to metric tons. Over years of dedicatedeffort, FDC has successfully synthesized thousands ofnew molecules and advanced pharmaceutical inter-mediates.And beyond that, we have capability tooffer over 100,000 research chemicals to clientsworldwide. We have established long-term partner-ship with pharmaceutical companies and researchinstitutes globally in Asia, Europe and North Americaetc. We have gained reputation in the industry as anexpertise in custom synthesis, contract research andmanufacturing with efficient operations and high-stan-dard quality control.
KEY CAPABILITIES
Years of unswerving commitment have empowered our R&D team to master pivotal core technologies andsecure essential patents. Our prowess extends to a robust command over R&D. pilot testing. and scale-upamplification in domains like pyridine, pyrimidine, and other heterocyclic compounds. Our dynamic team ofproficient professionals and experts serves as the cornerstone of our positive feedback loop within the R&Dindustrial chain. This dynamic ecosystem fortifies the bedrock upon which our diversified enterprises thriveensuring a trajectory of sustainable qrowth and innovation.
Established in 2010,SHANGHAI FDC-CHEMICALCO.,LTD, specializes in developing pharmaceuti-calsmall molecules and offers CRO &CDMOservices for the global pharmaceutical industry.We provide chemistry services from early drugR&D stage to commercial production, includingsmall scale building block synthesis, pilot-scaleand commercial manufacturing. Our goal is toexpedite the journey of our pharmaceutical partnersfrom preclinical phases to commercial production, byproviding such advanced products and services to theglobal industry.
Our unwavering pursuit is to achieve "Seamlesscollaboration with clients, effective communication,and fulfilling our mission." In the future, FDC willpersist in its business philosophy of "innovation" and"mutually beneficial cooperation," deeply engaging inthe research, development, services, and commercialproduction of novel molecular drugs. We aim to collab-orate with partners worldwide to foster excellence.
Our R&D Center, with space over 1700 square meters.has four fully equipped chemical synthesis laboratoriesand two kilo-lab units. Our dedicated team of over 30researchers has the capacity to simultaneously handlemore than 100 research projects. Our focus is the de.velopment of small molecules for novel drug candi-dates, especially anti-tumor drugs, from innovativesynthesis routes to verification and optimization of production process.Furthermore,our center isequipped with a cutting-edge analysis and testingfacility, a standardized quality control frameworkand an intricately managed warehousing anoogistics system,These comprehensive resourcescollectively contribute to enhancing our customersresearch and developmental processes.
|
General Description |
2,3,4,5-Tetrahydro-1H-benzo[d]azepine, also known as THBAP, is a heterocyclic chemical compound with a bicyclic structure. It is a derivative of the tricyclic antidepressant drug amoxapine and is used in the development of new pharmaceuticals. THBAP exhibits central nervous system activity and has been studied for its potential as a therapeutic agent for psychiatric and neurological disorders. It has also shown potential as an analgesic and anti-inflammatory agent. THBAP is a versatile molecule that has attracted interest in the field of medicinal chemistry for its broad range of pharmacological activities and potential therapeutic applications. |
InChI:InChI=1/C10H13N/c1-2-4-10-6-8-11-7-5-9(10)3-1/h1-4,11H,5-8H2
The discovery of new highly potent and s...
The invention relates to a compound as a...
Compounds of Formula I and their uses of...
New 7-sulfonamido-3-benzazepines 3 are d...
Use of compounds of general formula (1) ...
1,2-phenylenediacetonitrile
2,3,4,5-tetrahydro-1H-3-benzazepine
| Conditions | Yield |
|---|---|
|
With ammonia; hydrogen; nickel; In ethanol; at 50 ℃; for 24h; under 51714.8 Torr;
|
60% |
|
With ammonia; hydrogen; Raney Nickel; In methanol; at 70 ℃; for 48h; under 36201.3 Torr;
|
47% |
|
In ethanol; dichloromethane;
|
35% |
|
With hydrogen; nickel; In ethanol; at 50 ℃; for 24h; under 2585.81 Torr;
|
35% |
|
With ethanol; ammonia; nickel; at 100 ℃; under 55163.1 Torr; Hydrogenation;
|
|
|
With hydrogen; nickel; In ethanol; at 50 ℃; for 24h; under 2585.81 Torr;
|
2.45 g |
1,2-phenylenebis(ethane-2,1-diyl) dimethanesulfonate
2,3,4,5-tetrahydro-1H-3-benzazepine
| Conditions | Yield |
|---|---|
|
With ammonia; at 90 ℃; for 3h; Sealed tube;
|
100% |
|
1,2-phenylenebis(ethane-2,1-diyl) dimethanesulfonate; With ammonia; In water; acetonitrile; at 100 ℃; for 1h; under 2068.65 Torr;
With hydrogenchloride; water; In acetonitrile; pH=4;
With sodium hydroxide; In diethyl ether; water; acetonitrile; pH=14;
|
81% |
|
With ammonia; In ethanol; water; at 80 ℃; for 0.666667h; Microwave;
|
73% |
|
With ammonia; In acetonitrile; at 100 ℃; for 1h; under 2068.65 Torr; Autoclave;
|
20% |
1,2-phenylenediacetonitrile
ethanol
ammonia
3-formyl-2,3,4,5-tetrahydro-1H-3-benzazepine
3-benzyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine
1,2,4,5-tetrahydro-benzo[d]azepine-3-carboxylic acid methyl ester
2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylamine
methyl 7-amino-2,3,4,5-tetrahydro-1H-3-benzazepine-3-carboxylate