Shanghai FDC-CHEMICAL Co., Ltd.
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Country: 
China (Mainland)
Business Type:Trading Company
Tel: 86-21-61469567
Mobile:
Tel: 86-21-61469567
Fax: 86-21-61469151
URL: https://www.fdc-chemical.com/
Province/state: Shanghai
City: Shanghai
Street: Room 1101, Building A8, Lane 1688, North Guoquan Road, Yangpu District, Shanghai
MaxCard:
CAS NO.7724-12-1
Our R&D center is located in the Hongqiao Science andTechnology Innovation Park, Songjiang District, Shang-hai. The center is fully operated with four chemicalsynthesis laboratories and two kilo-lab laboratories.Our production facilities, located in Shandong, Jiang-su, and Hebei, are capable of handling the productionof advanced pharmaceutical intermediates, rangingfrom 100 kg to metric tons. Over years of dedicatedeffort, FDC has successfully synthesized thousands ofnew molecules and advanced pharmaceutical inter-mediates.And beyond that, we have capability tooffer over 100,000 research chemicals to clientsworldwide. We have established long-term partner-ship with pharmaceutical companies and researchinstitutes globally in Asia, Europe and North Americaetc. We have gained reputation in the industry as anexpertise in custom synthesis, contract research andmanufacturing with efficient operations and high-stan-dard quality control.
KEY CAPABILITIES
Years of unswerving commitment have empowered our R&D team to master pivotal core technologies andsecure essential patents. Our prowess extends to a robust command over R&D. pilot testing. and scale-upamplification in domains like pyridine, pyrimidine, and other heterocyclic compounds. Our dynamic team ofproficient professionals and experts serves as the cornerstone of our positive feedback loop within the R&Dindustrial chain. This dynamic ecosystem fortifies the bedrock upon which our diversified enterprises thriveensuring a trajectory of sustainable qrowth and innovation.
Established in 2010,SHANGHAI FDC-CHEMICALCO.,LTD, specializes in developing pharmaceuti-calsmall molecules and offers CRO &CDMOservices for the global pharmaceutical industry.We provide chemistry services from early drugR&D stage to commercial production, includingsmall scale building block synthesis, pilot-scaleand commercial manufacturing. Our goal is toexpedite the journey of our pharmaceutical partnersfrom preclinical phases to commercial production, byproviding such advanced products and services to theglobal industry.
Our unwavering pursuit is to achieve "Seamlesscollaboration with clients, effective communication,and fulfilling our mission." In the future, FDC willpersist in its business philosophy of "innovation" and"mutually beneficial cooperation," deeply engaging inthe research, development, services, and commercialproduction of novel molecular drugs. We aim to collab-orate with partners worldwide to foster excellence.
Our R&D Center, with space over 1700 square meters.has four fully equipped chemical synthesis laboratoriesand two kilo-lab units. Our dedicated team of over 30researchers has the capacity to simultaneously handlemore than 100 research projects. Our focus is the de.velopment of small molecules for novel drug candi-dates, especially anti-tumor drugs, from innovativesynthesis routes to verification and optimization of production process.Furthermore,our center isequipped with a cutting-edge analysis and testingfacility, a standardized quality control frameworkand an intricately managed warehousing anoogistics system,These comprehensive resourcescollectively contribute to enhancing our customersresearch and developmental processes.
|
General Description |
6-Amino-2-benzothiazolecarbonitrile is a chemical compound with the molecular formula C8H6N4S. It is a benzothiazole derivative, specifically an aminobenzothiazolecarbonitrile, and is commonly used in the synthesis of pharmaceuticals and agrochemicals. 6-Amino-2-benzothiazolecarbonitrile has a variety of applications, including as an intermediate in the production of dyes and pigments, as well as in the manufacturing of rubber chemicals and antioxidants. It is also used in the synthesis of biologically active compounds, making it an important building block for pharmaceutical research and development. Additionally, 6-Amino-2-benzothiazolecarbonitrile may have potential uses in other areas, such as material science and organic synthesis. |
InChI:InChI=1/C8H5N3S/c9-4-8-11-6-2-1-5(10)3-7(6)12-8/h1-3H,10H2
All known light-emitting firefly-biolumi...
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6-nitro-1,3-benzothiazole-2-carbonitrile
2-cyano-6-aminobenzothiazole
| Conditions | Yield |
|---|---|
|
With ammonium chloride; zinc; at 20 ℃; for 0.5h;
|
95% |
|
With iron; acetic acid; at 20 ℃; for 24h;
|
71% |
|
With iron; ammonium chloride; In tetrahydrofuran; methanol; water; at 70 ℃;
|
54% |
|
With stannous chloride; sodium hydrogencarbonate; In ethanol;
|
|
|
6-nitro-1,3-benzothiazole-2-carbonitrile; With tin(ll) chloride; In ethanol; at 60 ℃; for 2h; Inert atmosphere;
With sodium hydrogencarbonate; In ethanol; water; pH=7;
|
|
|
With ammonium chloride; zinc; Inert atmosphere;
|
2-chlorobenzothiazol-6-ylamine
potassium cyanide
2-cyano-6-aminobenzothiazole
| Conditions | Yield |
|---|---|
|
In dimethyl sulfoxide; at 120 ℃;
|
54% |
|
In dimethyl sulfoxide;
|
2-chlorobenzothiazol-6-ylamine
potassium cyanide
6-nitro-1,3-benzothiazole-2-carbonitrile
6-nitrobenzo[d]thiazole
6-((4-benzyloxycarbonylaminophenyl)ethylamino)-2-cyanobenzothiazole
tert-butyl 2-(2-cyanobenzo[d]thiazol-6-ylamino)-2-oxoethylcarbamate
tert-butyl 1-(2-(2-cyanobenzo[d]thiazol-6-ylamino)-2-oxoethylamino)-1-oxo-3-(tritylthio)propan-2-ylcarbamate
tert-butyl 1-(2-cyanobenzo[d]thiazol-6-ylamino)-1-oxo-3-(tritylthio)propan-2-ylcarbamate